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hamp  (Novus Biologicals)


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    Structured Review

    Novus Biologicals hamp
    Hamp, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hepcidin+antimicrobial+peptide+antibody/Hepcidin+Antimicrobial+Peptide+Antibody/10__1016_slash_j__psyneuen__2025__107279-94-13-14
    Average 93 stars, based on 10 article reviews
    hamp - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Isolation:

    Article Title: Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Western Blot:

    Article Title: Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Expressing:

    Article Title: Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Immunohistochemistry:

    Article Title: Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Mutagenesis:

    Article Title: Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.

    Article Title: Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer
    Article Snippet: KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.KRAS (sc-30), p53 (sc-126 for human), a-Tubulin (sc-8035) antibodies were from Santa Cruz Biotechnology.. Hepcidin Antimicrobial Peptide antibody (NBP1-59337) was from Novus Biologicals.. Actin (A2066) was from Sigma-Aldrich.Actin (A2066) was from Sigma-Aldrich.



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    Image Search Results


    Efficacy of targeting ALK2 in LKB1-mutant lung cancer in vivo. LKB1 restricts iron homeostasis pathways using a kinase-dependent mechanism. A, Mean tumor volume from syngeneic mice (JK-M cells) treated with vehicle (6 mice/group) and LDN214117 (7 mice/group). B, Graph depicting the mean tumor weight from vehicle- and LDN214117-treated mice. C, Brightfield images of tumors isolated from vehicle- and LDN214117-treated mice. D, The mean tumor volume from NSG mice with A549 lung tumor xenografts treated with either vehicle (7 mice/group), LDN214117 (7 mice/group), or LDN193189 (7 mice/group). E, Graph depicting the mean tumor weight from vehicle-, LDN214117-, and LDN193189-treated mice. F, Brightfield images of A549 tumors isolated from vehicle-, LDN214117-, and LDN193189-treated mice. G, Representative brightfield images of tumor sections treated with vehicle or LDN214117 and stained by the indicated Ab IHC or special stain. Scale bar, 200 μm or 2 mm (TUNEL). H, Western blot to assess BMP6 and hepcidin levels in tumors from vehicle- and LDN214117-treated mice. I, Western blot of indicated proteins from JK43-M cells treated with 1 uM of LDN214117 for 24, 48, and 72 hours. J, Western blot analysis of indicated proteins in vector, LKB1-WT, or LKB1-K78I add-back H157 lung cancer cells. K, Model depicting the mechanism of altered iron homeostasis signaling in LKB1-mutant tumor cells. **, P < 0.01; ****, P < 0.0001.

    Journal: Cancer Research

    Article Title: Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1 -Mutant Lung Cancer

    doi: 10.1158/0008-5472.CAN-23-2631

    Figure Lengend Snippet: Efficacy of targeting ALK2 in LKB1-mutant lung cancer in vivo. LKB1 restricts iron homeostasis pathways using a kinase-dependent mechanism. A, Mean tumor volume from syngeneic mice (JK-M cells) treated with vehicle (6 mice/group) and LDN214117 (7 mice/group). B, Graph depicting the mean tumor weight from vehicle- and LDN214117-treated mice. C, Brightfield images of tumors isolated from vehicle- and LDN214117-treated mice. D, The mean tumor volume from NSG mice with A549 lung tumor xenografts treated with either vehicle (7 mice/group), LDN214117 (7 mice/group), or LDN193189 (7 mice/group). E, Graph depicting the mean tumor weight from vehicle-, LDN214117-, and LDN193189-treated mice. F, Brightfield images of A549 tumors isolated from vehicle-, LDN214117-, and LDN193189-treated mice. G, Representative brightfield images of tumor sections treated with vehicle or LDN214117 and stained by the indicated Ab IHC or special stain. Scale bar, 200 μm or 2 mm (TUNEL). H, Western blot to assess BMP6 and hepcidin levels in tumors from vehicle- and LDN214117-treated mice. I, Western blot of indicated proteins from JK43-M cells treated with 1 uM of LDN214117 for 24, 48, and 72 hours. J, Western blot analysis of indicated proteins in vector, LKB1-WT, or LKB1-K78I add-back H157 lung cancer cells. K, Model depicting the mechanism of altered iron homeostasis signaling in LKB1-mutant tumor cells. **, P < 0.01; ****, P < 0.0001.

    Article Snippet: Hepcidin antimicrobial peptide Ab (NBP1-59337) was from Novus Biologicals.

    Techniques: Mutagenesis, In Vivo, Isolation, Staining, TUNEL Assay, Western Blot, Plasmid Preparation